Boulder

Description
A boulder, Chris Redfield's enemy since times immemorial, he has trained his muscles for the express purpose of destroying them.

Season 5
Kotomine Kirei conjures a boulder through magecraft to get rid of Date Kaname and Raiden, but Chris intercepts the boulder, saving them, but by the boulder's magical nature he couldn't destroy it in time and was killed.

Season 0
The boulder returns in a dungeon inside Dan's Van has it's rematch with Chris, where he easily blows it into smithereens with a single punch, without even being awake.